Clinical efficacy of intensity modulated radiotherapy syn -chronization TP chemotherapy combined with af-terloading radiotherapy for advanced cervical cancer
10.3760/cma.j.issn.1008-6706.2015.12.033
- VernacularTitle:调强放疗结合腔内后装放疗联合 TP 方案化疗治疗中晚期宫颈癌临床观察
- Author:
Wenbing ZHANG
;
Tongfang XIE
;
Jun TANG
- Publication Type:Journal Article
- Keywords:
Radiation therapy;
Drug therapy,combination;
Cervical cancer
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(12):1859-1861
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical efficacy and adverse reactions of intensity modulated radio-therapy(IMRT)syn -chronization TP chemotherapy combined with afterloading radiotherapy for advanced cervical cancer.Methods 58 cases of advanced cervical cancer patients were randomly divided into the chemotherapy combi-nation with radiotherapy(observation group,30cases)and radiotherapy alone(control group,28cases),Both groups were treated with external IMRT combined with afterloading radiotherapy,patients of the observation group were accepted concurrent chemoradiotherapy for TP regimen,and the patents of the control group were only accepted radio-therapy,the short -term curative effect,adverse reactions of the two groups were compared.Results The effective rate of the control group was 71.4%,which of the observation group was 83.3%.the observation group short -term curative effect was better than that of control group,with a significant difference(χ2 =4.247,P <0.05),whereas the incidence rates of radiation cystitis,radiation proctitis,myelosuppresson and digestive tract reaction were not signifi-cantly different between two groups(P >0.05)no serious.Conclusion It can allow the patients with advanced cervi-cal cancer to benefit from the concurrent chemoradiotherapy.
