Analysis of transient elastography technique on the degree of chronic hepatitis B fibrosis

VernacularTitle:瞬时弹性成像技术检测慢性乙型肝炎纤维化程度分析
Author: Xuefeng ZHANG ; Chun XU ; Wei WANG
Publication Type:Journal Article
Keywords: Elasticity imaging techniques; Hepatitis B,chronic; Liver cirrhosis
From: Chinese Journal of Postgraduates of Medicine 2014;37(28):17-19
CountryChina
Language:Chinese
Abstract: Objective To explore the practical value of liver transient elastography technique in the detection of chronic hepatitis B fibrosis.Methods The liver biopsy and transient elastography technique was detected in 106 patients with chronic hepatitis B.Observation index included:alanine aminotransferase (ALT),aspartate aminotransferase (AST),total bilirubin (TBIL),albumin (ALB),platelet (PLT),statistial analysis was performed in liver biopsy and fibroscan results by SPSS17.0 software.Results Liver stiffness measurement (LSM) was positively correlated with ALT,AST and TBIL,and which was negatively correlated with ALB,PLT,and which was positively correlated with liver fibrosis stage.The area under the ROC curve by the LSM prediction of liver fibrosis S4,S3,S2 stage were 0.869 (95％ CI 0.809-0.918),0.841 (95％ CI 0.810-0.901),0.806 (95％ CI 0.747-0.866),the corresponding critical value was 22.9,14.8,10.2 kPa.Conclusion There is a good correlation between fibroscan and liver fibrosis,LSM ＞ 10.2 kPa can be considered in patients with antiviral therapy.