Vitamin D and the recurrence of rheumatoid arthritis
10.3760/cma.j.issn.1673-4904.2015.07.011
- VernacularTitle:维生素D对类风湿关节炎复发率的影响
- Author:
Junxia YANG
;
Lin LIU
;
Qinglin ZHANG
;
Meirong LI
;
Jingya WANG
- Publication Type:Journal Article
- Keywords:
Vitamin D;
Recurrence;
Arthritis,rheumatoid;
Randomized controlled trial
- From:
Chinese Journal of Postgraduates of Medicine
2015;38(7):506-508
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify the correlation between vitamin D prescription and recurrence in rheumatoid arthritis (RA).Methods A randomized controlled trial study was performed in 170 RA patients who were in remission during the past 2 months.According to the level of vitamin D,170 RA patients were divided into normal vitamin D group (84 patients) and deficiency vitamin D group (86 patients).Deficiency vitamin D group were randomly allocated to receive vitamin D treatment(vitamin D treatment group) or without vitamin D treatment (control group).In the 6-month follow-up period,the recurrence status was observed and compared.Results In the 6-month follow-up period,the recurrence rate of RA in normal vitamin D group was 16.7％(14/84),in vitamin D treatment group was 19.0％(8/42) and in control group was 29.5％(13/44),and there was no significant difference (P ＞ 0.05).In vitamin D treatment group,no hypercalcemia and hyperphosphatemia occured.The age,course of disease and remission time in recurrence patients of three groups were no significant difference (P ＞ 0.05).The level of vitamin D in recurrence patients of vitamin D treatment group was higher than that in recurrence patients of control group:(25.5 ± 8.9) ng/L vs.(20.9 ± 8.6)ng/L,and there was significant difference(P＜ 0.05).Conclusion Vitamin D deficiency is not identified to be a risk factor for RA recurrence.Vitamin D does not reduce the recurrence of RA.
