Analysis on the function of stereotactic radiation therapy and whole-brain radiation therapy in treatment of multiple brain metastasis tumor
10.3760/cma.j.issn.1673-4904.2015.06.003
- VernacularTitle:立体定向放疗与全脑放疗在多发脑转移瘤治疗中的作用分析
- Author:
Feng CHEN
;
Jianfei JIANG
;
Liyong JIANG
- Publication Type:Journal Article
- Keywords:
Neoplasm metastasis;
Radiosurgery;
Radiotherapy,computer-assisted;
Survival time
- From:
Chinese Journal of Postgraduates of Medicine
2015;38(6):397-400
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the function of stereotactic radiation therapy (SRT) and wholebrain radiation therapy (WBRT) in treatment of multiple brain metastasis tumor.Methods Fifty-two patients with multiple brain metastasis tumor were retrospectively analyzed.The patients were divided into simple stereotactic radiation therapy group (22 cases) and whole-brain radiation therapy + stereotactic radiation therapy group (30 cases) according to the radiation therapy method.The median overall survival time and distant brain tumor recurrence rate in 1 year etc.were compared between 2 groups.Results There were no statistical differences in the median overall survival time and fatality rate between simple stereotactic radiation therapy group and whole-brain radiation therapy + stereotactic radiation therapy group:13.0 months (95％ CI 8.05-27.84) vs.13.4 months (95％ CI 8.57-19.48),86.36％ (19/22) vs.86.67％ (26/30),P＞ 0.05.The distant brain tumor recurrence rate in 1 year in simple stereotactic radiation therapy group was significantly higher than that in whole-brain radiation therapy + stereotactic radiation therapy group:45.45％ (10/22) vs.20.00％ (6/30),and there was statistical difference (x2 =3,861,P =0.049).Conclusion Stereotactic radiation therapy and whole-brain radiotherapy can achieved similar median overall survival time.
