Comparison of effects of etomidate and propofol on cardiac and renal function in perioperative elderly patients
- VernacularTitle:围手术期应用依托咪酯与异丙酚对老年肿瘤患者心、肾功能影响的比较
- Author:
Haibin WANG
;
Lili ZOU
;
Hongxing MIN
- Publication Type:Journal Article
- Keywords:
etomidate;
propofol;
cardiac function;
renal function
- From:
Chinese Journal of Biochemical Pharmaceutics
2015;(6):105-107
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effect of etomidate and propofol on cardiac and renal function in perioperative elderly patients. Methods 120 perioperative elderly patients were selected and divided into two groups.60 cases in etomidate group (T group) were anesthesia induced by etomidate, and 60 cases in propofol group ( B group) were anesthesia induced by propofol.Hemodynamics, renal function and perioperative indexes were compared after operation.Results Compared with before induction, SBP, DBP and HR were lower after induction(P<0.05), and compared with T group at the same time, SBP, DBP and HR of B group were lower( P<0.05).Compared with before induction, SI, CI and EV were lower after induction (P<0.05), and compared with T group at the same time, SI, CI and EV of the B group were lower(P<0.05).Compared with B group, Cr, BUN and β2-MG of T group were lower ( P<0.05 ) .Conclusion The effects of etomidate on inhibition of cardiovascular system and damage of renal function is slighter, which has important significance for elderly cancer patients.
