RGC-32 involving in cell cycle regulation
10.3760/cma.j.issn.1673-4408.2014.06.007
- VernacularTitle:RGC-32与细胞周期调控
- Author:
Huajie LIU
- Publication Type:Journal Article
- Keywords:
RGC-32;
Cell cycle regulation;
G2/M check point;
Cell proliferation and differentiation
- From:
International Journal of Pediatrics
2014;41(6):598-600
- CountryChina
- Language:Chinese
-
Abstract:
As one of the important response gene to complement,response gene to complement-32 (RGC-32) simultaneously involves in many other biological functions.Recent studies have shown that RGC-32 was one of the critical regulatory factors at the G2/M check point in the cell cycles and involved in the cell cycle regulation.The expression products of RGC-32 gene play the key roles in cell proliferation,differentiation,inflammation,tumor metastasis and other processes.However,it has not been clarified in its biological mechanisms of regulation in cell cycle.This article takes a brief review about RGC-32 on its gene structure,biological functions,regulation of cell cycle,and the relationship of cell cycle regulation which involves in RGC-32.