The efficacy and safety analysis for endoscopic multi-band mucosectomy in the treatment of early esophageal cancer and intraepithelial neoplasia
10.3760/cma.j.issn.1673-4904.2015.07.012
- VernacularTitle:新型多环黏膜套切术治疗食管早癌和上皮内瘤变的疗效和安全性分析
- Author:
Tong LI
;
Yanqin WEI
;
Shuyun WANG
;
Bochao ZHAO
;
Xiaomei ZHANG
- Publication Type:Journal Article
- Keywords:
Esophageal neoplasms;
Intraepithelial neoplasia;
Multi-band mucosectomy
- From:
Chinese Journal of Postgraduates of Medicine
2015;38(7):509-512
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the safety and efficacy of endoscopic multi-band mucosectomy (EMBM) in the treatment of early esophageal cancer and intraepithelial neoplasia.Methods A retrospective analysis was made on the clinical data of 34 cases diagnosed with early esophageal cancer and intraepithelial neoplasia.All the patients accepted EMBM.The therapeutic effects and safety were summarized.Results A total of 34 patients with 36 lesions were successfully completed in the treatment of one session.The entire biopsy specimen was tested by pathological examination.High-grade intraepithelial neoplasia in 24 lesions,low-grade intraepithelial neoplasia in 4 lesions,intramucosal cancer in 6 lesions,a submucosal shallow cancer and a submucosal deep cancer were diagnosed.Clamps electric coagulation hemostasis was used during the operation in 2 bleeding cases.No delayed postoperative bleeding,subcutaneous emphysema and esophageal perforation happened.Two cases appeared esophageal stenosis after EMBM.Bougienage were used to relieve dysphagia.One case confirmed with deep submucosal lymphovascular invasion accepted surgery later in department of thoracic surgery.No local recurrence and metastasis were found in the other 33 cases during the 6-24 months of follow-up time.Conclusions EMBM is a minimally invasive,safe and effective method for the treatment of early esophageal cancer and intraepithelial neoplasia.EMBM is worthy of promotion.
