Effect of Qi-ming granule on multifocal ERG(mfERG) of patients with mild, moderate non-prolif-erative diabetic retinopathy (NPDR)
- VernacularTitle:芪明颗粒对轻、中度非增殖期糖尿病视网膜病变患者多焦视网膜电图的影响
- Author:
Wenzhou LIU
;
Yani LIU
;
Junguo DUAN
;
Xuejing LU
- Publication Type:Journal Article
- Keywords:
Qi-ming granule;
Multifocal electroretinogram,mf-ERG;
Diabetic retinopathy,DR
- From:
Journal of Chinese Physician
2015;(z1):33-36
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate effect of Qi-ming granule on vision function of patients with mild, moderate non-proliferative diabetic retinopathy ( NPDR ) .Methods Using the randomized double blind and placebo-controlled clinical trial method.From Oct.2012 to Jun.2014, 36 patients with 68 eyes who included in the standard were randomly divided into treatment group,control group,given Qi-ming gran-ule and placebo respectively for 6 months, exam with mfERG before treatment and after treatment, evaluate the curative effect.Results After 6 months treatment of Qi-ming granule, the implicit time of the 4th ring of the N1 wave about the mfERG was shorter than that of preoperative( P <0.05), the amplitude density was more than both that of preoperative and control group( P <0.01), the amplitude density of the 5th ring increased compared to that of control group;The peak latency of 3 rd ring of P1 wave was shorter than that of control group( P <0.01), the amplitude density of 1st,3rd,5th ring restored compared with that of preopera-tive and control group( P <0.01), the amplitude density of 4th ring improve than that of control group( P<0.01).Conclusions Qi-ming granule can improve the multifocal ERG of patients with mild, moderate non-proliferative diabetic retinopathy, restore the vision function.
