Expression of TSLC-1 in human papillary thyroid carcinoma and its clinical significance
10.3969/j.issn.1006-5725.2015.12.007
- VernacularTitle:TSLC-1在甲状腺乳头状癌组织中的表达及临床意义
- Author:
Hua HU
;
Shuai YANG
;
Xiaoyu WANG
- Publication Type:Journal Article
- Keywords:
TSLC-1;
Papillary thyroid carcinoma;
Immunohistochemistry
- From:
The Journal of Practical Medicine
2015;(12):1922-1925
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between TSLC-1 protein expression and the progression and carcinogenesis of human papillary thyroid carcinogenesis. Methods Expressions of TSLC-1 protein in 20 pieces of benign thyroid lesions and 40 pieces of papillary thyroid carcinoma tissues were examined by immunohistochemistry. Results The expression of TSLC-1 in papillary thyroid carcinoma (9/40) was lower than that in benign thyroid lesions (22.50% versus 90.00%, P < 0.05). Expression of TSLC-1 was significantly associated with lymph node metastasis and TNM in papillary thyroid carcinoma (P < 0.05). Conclusions Expression of TSLC-1 is closely related with carcinogenesis , lymph node metastasis , and clinical stage in papillary thyroid carcinoma.
