Effect of baseline left ventricular ejection fractions impact on the outcome of cardiac resynchronization therapy in patients with heart failure
10.3969/j.issn.1006-5725.2015.12.012
- VernacularTitle:心衰患者基础左室射血分数影响心脏再同步化治疗疗效的分析
- Author:
Xiaochen WANG
;
Zhangle HU
;
Jianlong SHENG
;
Banglong XU
;
Jixiong WU
- Publication Type:Journal Article
- Keywords:
Heart failure;
Cardiac resynchronization therapy;
Left ventricular ejection fractions
- From:
The Journal of Practical Medicine
2015;(12):1939-1941
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of baseline Left-ventricular ejection fraction (LVEF) on the cardiac resynchronization therapy (CRT). Methods A retrospective analysis of patients with heart failure was performed. Fifty-four patients [aged (59.73 ± 11.61)years, 31 males, 23 females] who underwent CRT/CRTD were divided into 2 groups according to LVEF ( group A, LVEF≤ 35%; group B, LVEF > 35% ). NYHA class, LVEF,CRT respond rates and medical adverse event (MAE) due to worsening heart failure were detected at 3 and 12 months post-surgery. Results The score of NYHA class changing wasn′t different between these two group. Compared to group B, LVEF was markedly increased (5.08 ± 2.81)% vs (2.45 ± 1.80)%, P < 0.05;(5.38 ± 2.92)% vs (2.39 ± 3.53)%, P < 0.05)at 3 and 12 months post-surgery. Similarly, group A owned high CRT response rates(66.1% vs 33.9%, P < 0.05; 81.25% vs 47.83%, P < 0.05) at the both two time points. At 12 months post-surgery , LVED decreased and the MAE was similar in all groups. Conclusion Patients with EF≤ 35% have more increases in LVEF and own high CRT response rates post-CRT.
