Comparison of breath-hold and respiratory-triggered proton MR spectroscopy in quantification of liver fat content
10.3969/j.issn.1006-5725.2015.12.016
- VernacularTitle:屏气与呼吸触发氢质子磁共振波谱量化肝脏脂肪含量的比较
- Author:
Chulan LIN
;
Guihua JIANG
;
Jinwu LIU
;
Wuming LI
;
Jianhao YAN
;
Lianbao LIANG
;
Xianyue QUAN
- Publication Type:Journal Article
- Keywords:
Magnetic resonance spectroscopy;
Liver fat quantification;
Nonalcoholic fatty liver disease;
Respiratory-triggered;
Breath-hold
- From:
The Journal of Practical Medicine
2015;(12):1951-1953
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the consistency and correlation of multiple breath-hold (BH) with respiratory-triggered (RT) 1H-MRS for quantification of hepatic lipid content. Methods Sixty subjects were underwent RT 1H-MRS of the liver (Couinaud segment VII) and BH 1H-MRS at 1.5 Tesla Magnetic Resonace Imaging (MRI). The peak areas of water and methylene obtained on RT and BH 1H-MRS were recorded respectively and the liver fat fraction was calculated. Pearson correlation coefficient , Bland-Altman 95% limit of agreement, and concordance correlation coefficient were calculated. Results Mean liver fat fraction measured in RT and BH 1H-MRS were (8.6 ± 8.7)% and (9.4 ± 9.3)% respectively. There was a strong correlation between RT and BH 1H-MRS(r = 0.973, P < 0.000 1, concordance correlation coefficient = 0.95). With the Bland-Altman method, 91.7% data points were within the 95% limits of agreement. Conclusion RT and BH 1H-MRS are alternative tools for intrahepatic lipid quantification. These two methods have a strong correlation and perfect consistency.
