Curative effect of radiofrequency ablation combined with chemotherapy on middle-late stage non-small cell lung cancer
10.3969/j.issn.1006-5725.2015.11.019
- VernacularTitle:经皮射频消融联合化疗治疗Ⅲb～Ⅳ期非小细胞肺癌的疗效
- Author:
Jingxu ZHOU
;
Hong LI
;
Wenjiao LV
;
Shutang WANG
;
Xinting ZHENG
;
Lizhu LIN
- Publication Type:Journal Article
- Keywords:
Non-small cell lung cancer;
Radiofrequency ablation;
Chemotherapy
- From:
The Journal of Practical Medicine
2015;(11):1786-1789
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical curative effect of Ⅲb~Ⅳstage non-small cell lung cancer treated by radiofrequency ablation combined with chemotherapy. Methods Forty-eight Ⅲb~Ⅳstage non-small cell lung cancer patients were divided into the study group (RFA + chemotherapy) and 74 were in control group (chemotherapy alone) by the method of non randomized controlled. Curative effect was evaluated every two cycles during the treatment. A 6 to 36 months follow-up was conducted after the treatment. Results The objective response rate of experiment group and control group was 58.3%and 41.9%respectively (P>0.05) with no significant difference and disease control rates of experiment group and control group were 91.7% and 75.7% respectively (P<0.05). MST were 14.4 months and 8.2 months respectively (P<0.01), with statistically significant differences in experiment group and control group and clinical benefit efficient were 87 . 5% and 66 . 2% respectively ( P < 0.05). Conclusion The treatment of radiofrequency ablation combined with chemotherapy for advanced non-small cell lung cancer can significantly improve the patient′s survival and the clinical curative effect.
