Application of three-dimensional cell culture model in cancer research
10.3760/cma.j.issn.1673-422X.2015.07.015
- VernacularTitle:三维细胞模型在肿瘤实验中的应用
- Author:
Fei FENG
;
Songbing QIN
- Publication Type:Journal Article
- Keywords:
Neoplasm metastasis;
Cell culture techniques;
Tumor microenvironment
- From:
Journal of International Oncology
2015;(7):532-534
- CountryChina
- Language:Chinese
-
Abstract:
Three-dimensional cell culture is widely recognized as a model in vitro that can better simu-late the interaction between tumor cells in vivo and cell microenvironment. Compared with the traditional two-dimensional cell culture,it has obvious advantages in the study of the observation of tumor cells biological be-havior,tumor resistance,radiation insensitivity,gene expression in vivo and in other aspects of the study. It can provide a valuable model in vitro for experimental study on the basis of tumor.