Effects of inflammatory cytolines on sevoflurane combined with remifentanil on general anesthesia in cesarean operation
10.3969/j.issn.1006-5725.2015.11.035
- VernacularTitle:七氟醚联合瑞芬太尼用于产科全身麻醉对炎性细胞因子的影响
- Author:
Jie JIA
;
Yi LI
;
Zurong HU
;
Zaomei WEI
- Publication Type:Journal Article
- Keywords:
Caesarean section;
General Anesthesia;
IL-6;
TNF-α;
sTNFRⅡ;
Sevoflurane;
Remifentanil
- From:
The Journal of Practical Medicine
2015;(11):1832-1834
- CountryChina
- Language:Chinese
-
Abstract:
Objective To examine plasma inflammatory cytokines and assess stress response in different general anesthesia schemes in cesarean operation. Methods Sixty caesarean operation puerperas were randomly divided into two groups, including the group of sevoflurane (Group S) and the group of propofolum (Group P) in 30 cases of each group. At different time point, we recorded the mean arterial pressure and heart rate, text the blood concentration of inflammatory cytokines; The Apgar scores and arteria umbilicalis pH value after baby delivery were recorded. Results The blood pressure and heart rate of the P group after anesthesia induction of baby in delivery were lower than that before the anesthesia induction(P < 0.05). And there were also significant differences when compared with the S group (P < 0.05). The blood concentration of IL-6 and TNF-α of the P group afte operation were higher than that before the anesthesia induction(P < 0.05). There were also significant differences when compared with the S group(P < 0.05). The blood concentration of sTNFRⅡof the P group after operation and 24 hours after the surgery were higher than that before the anesthesia induction (P < 0.05). And there were also significant differences when compared with the S group (P < 0.05). Conclusion Administering Sevoflurane compound with Remifentanil to general anesthesia in Caesarean operation is safty and steady to inhibit stress reaction and prevent explicit memory from the operation.
