Sheng-qi-zhuang-yang formula combined with specific immunotherapy with standardized house dust mite vaccine on allergic asthmatic children：A preliminary effect and safety assessment
10.3969/j.issn.1006-5725.2015.11.044
- VernacularTitle:升气壮阳方联合标准化屋尘螨疫苗免疫治疗儿童变应性哮喘的临床疗效及安全性评价
- Author:
Yanxia ZHENG
;
Zhuoxun LIU
;
Bingjie LI
;
Wenwen JIANG
;
Youjia XU
- Publication Type:Journal Article
- Keywords:
Allergic asthma;
Sheng-qi-zhuang-yang decoction/formula;
Children;
House dust mite;
Immunotherapy
- From:
The Journal of Practical Medicine
2015;(11):1855-1858
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and safety of Sheng-qi-zhuang-yang formula combined with specific immunotherapy (SIT) with standardized house dust mite vaccine on allergic asthmatic children. Methods Participants were 100 children with mild to moderate allergic asthma , who were receiving SIT at Guangdong Provincial Hospital of Chinese Medicine from Jan 2011 to Dec 2013 , who were divided into treatment group and control group. Patients in the treatment group received Sheng-qi-zhuang-yang Decoction combined with SIT while patients in the control group received SIT alone. Asthma symptom scores, respiratory function and related adverse events were compared before and after treatment, between groups. Results The desensitization treatment functions was ahead of time than expected in both groups. There is no significant difference between groups in terms of respiratory function and adverse effects. Conclusion Sheng-qi-zhuang-yang decoction combined with SIT for allergic asthmatic children seems to advance clinical effect without increasing adverse events. Further large scale clinical trial is required to confirm this.
