Insulin resistance in first-degree relatives of patients with Graves disease
10.3969/j.issn.1006-5725.2015.12.014
- VernacularTitle:Graves 病合并糖代谢异常一级亲属胰岛素抵抗研究
- Author:
Zhengrong XU
;
Ming LIU
;
Haifeng SUN
;
Jun GU
;
Li SHI
- Publication Type:Journal Article
- Keywords:
Diabetes mellitu;
Graves disease;
First-degree relatives;
Insulin resistance
- From:
The Journal of Practical Medicine
2015;(12):1945-1947
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe insulin resistance in first-degree relatives of patients with Graves disease. Methods All subjects in control group and experiment group including first-degree relatives of GD patients underwent oral glucose tolerance tests (OGTT) and insulin releasing tests then the degree of insulin resistance was analyzed. Results Blood glucose at each point of OGTT, insulin level and insulin resistance index 1 (HOMA-IR) of experiment group were higher than those in control group, while insulin activity index (IAI) and HOMA-βwere significantly lower than those in control group. Conclusion Patients insulin resistance could be found among first-degree relatives of GD patients.
