Sodium deoxyribonucleotide injection atZusanlipoint for chemotherapy-induced leukopenia in patients with lung cancer
10.3760/cma.j.issn.1673-4246.2015.07.007
- VernacularTitle:脱氧核苷酸钠穴位注射治疗肺癌化疗后白细胞减少症临床观察
- Author:
Lixing YANG
;
Dong WANG
;
Xuehai LI
;
Chenchen MA
;
Jianxin ZHANG
- Publication Type:Journal Article
- Keywords:
Leukopenia;
Antineoplastic agents;
Lung neoplasms;
Point ST36(Zusanli);
Deoxyribonucleotides;
Point injection
- From:
International Journal of Traditional Chinese Medicine
2015;(7):602-604
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate thetherapeutic effect of sodium deoxyribonucleotide injection at Zusanli point for chemotherapy-induced leukopenia in patients with lung cancer.MethodsA total of 116 chemotherapy-induced leukopenia patients with lung cancer were randomly divided into a therapy group and a control group, 60 in the treatment group and 56 in the control group. The patients in the treatment group were treated with sodium deoxyribonucleotide injection atZusnlipoint, and those in the control group were treated with vein injection of sodium deoxyribonucleotide.Results The total effective rate in the treatment group was significant higher than that in the control group (91.7%vs.76.8%;χ2=4.890,P=0.032). The effective rates on days 3,5,7 and 10 in the treatment group were also significant higher than those in the control group (on day 3: 51.7%vs. 32.1%,χ2=4.530,P=0.036; on day 5: 76.7%vs. 53.6%,χ2=6.840,P=0.018; on day 7: 85.0%vs. 67.9%,χ2=4.770,P=0.026; on day 10: 78.3%vs. 53.6%,χ2=7.960,P=0.011).Conclusion Sodium deoxyribonucleotide injection atZusanlipoint has definite efficacy for chemotherapy-induced leukopenia in patients with lung cancer.