Drug resistance and department distribution of Mycobacterium tuberculosis in a county-level hospital
10.3969/j.issn.1671-9638.2015.06.007
- VernacularTitle:某县级综合医院结核分枝杆菌耐药性及院内暴露科室分布
- Author:
Chunming SHEN
;
Qiaozhen WU
;
Wenying WU
;
Xiaoyan NI
;
Hao SHEN
- Publication Type:Journal Article
- Keywords:
lung;
tuberculosis;
Mycobacterium tuberculosis;
multidrug resistance;
drug resistance,microbial;
infection control
- From:
Chinese Journal of Infection Control
2015;(6):386-388
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore drug resistance and distribution of multidrug-resistant(MDR)Mycobacterium tuberculosis (M.tuberculosis)in a county-level hospital,so as to strengthen the prevention and control of health-care-associated infection with M.tuberculosis .Methods Specimens with positive sputum smear were performed M. tuberculosis culture and drug resistance testing,and distribution of MDR tuberculosis patients in the departments before isolation were investigated retrospectively.Results Of 488 patients with tuberculosis,254 were positive for sputum smear,122 M.tuberculosis strains were isolated from positive sputum smear patients,120 isolates were per-formed drug susceptibility testing,results revealed that 86 isolates were drug-resistant strains,46 of which were monodrug-resistant,40 were MDR.Of MDR strains,16 were all resistant to isoniazide,rifampicin,streptomycin, and ethambutol.The percentage of monodrug-resistance,MDR,pandrug resistance was 9.43%,8.20%,and 3.28% respectively.Medical imaging department,ultrasound department,and respiratory disease department were the main units of M.tuberculosis exposure.Conclusion The percentage of MDR M.tuberculosis is high among M. tuberculosis ,surveillance should be intensified,so as to prevent the transmission in hospital.