Research progress on hepatitis C virus-related cryoglobulinemia
10.3760/cma.j.issn.1674-2397.2015.03.025
- VernacularTitle:丙型肝炎病毒相关冷球蛋白血症研究进展
- Author:
Zhantao ZHU
;
Fuying MA
;
Junying ZHOU
;
Xiaoshuang ZHOU
- Publication Type:Journal Article
- Keywords:
Hepatitis C;
Cryoglobulinemia;
Pathogenesis;
Interferons
- From:
Chinese Journal of Clinical Infectious Diseases
2015;12(3):283-286
- CountryChina
- Language:Chinese
-
Abstract:
Chronic hepatitis C virus ( HCV) infection has been reported in association with several extrahepatic complications, among which mixed cryoglobulinemia is the most documented. Clinical manifestations of HCV related cryoglobulinemia include skin lesions, glomerulonephritis, peripheral neuropathy, and widespread vasculitis.The therapy may be directed to eradicate HCV infections, suppress B-cell clonal expansion and cryoglobulin production, and ameliorate symptoms.This paper reviews the research progress on pathogenesis, clinical manifestations, diagnosis and treatment of HCV related cryoglobulinemia.