Research progress of microRNAs in colorectal cancer therapy
10.3760/cma.j.issn.1673-422X.2015.05.019
- VernacularTitle:微小 RNA 在结直肠癌治疗中的研究进展
- Author:
Xiaojing LIN
;
Jingjing XU
;
Yan CHEN
- Publication Type:Journal Article
- Keywords:
MicroRNAs;
Colorectal neoplasms;
Targeted therapy
- From:
Journal of International Oncology
2015;(5):388-391
- CountryChina
- Language:Chinese
-
Abstract:
The molecular targeted therapy method using microRNAs(miRNAs)is gradually stepping into people′s vision. miRNAs affect colorectal cancer progress via abnormal expression in tumor cells or micro-environment. The high or low expressions of miRNAs in specific tissues probably have an impact on the expressions of oncogenes,tumor suppressor genes or other aspects including the surrounding environments,the metastases and the drug tolerance of tumors,thus contributing to curing the colorectal cancer. Nowadays, miRNA has entered the stage of animal experiments.
