Application of suckling mice in pediatric pharmacological and toxicological studies
10.3969/j.issn.1671.7856.2015.006.014
- VernacularTitle:浅谈乳鼠在儿童药药理毒理学研究中的应用
- Author:
Chengyu PIAO
;
Min YU
;
Yongwu LIU
;
Shumin LIU
- Publication Type:Journal Article
- Keywords:
Pediatric drugs;
Suckling mice;
Pharmacology;
Children;
Toxicology
- From:
Chinese Journal of Comparative Medicine
2015;(6):71-74
- CountryChina
- Language:Chinese
-
Abstract:
Research on laboratory animals is an important issue in biomedicine.Children are a special drug-using population.The selection of suitable experimental animals is a key issue to ensure the scientific quality of research for pediatric drugs.Based on the review of a large number of literature, the authors summarized the application of suckling mice in the pharmacological research and toxicological evaluation of pediatric drugs for the treatment of common diseases in children.We also summarized the existing problems in pediatric toxicology and proposed solutions for providing a reference of test animal application in pediatric drug research.