The long-term effect of iodine-131 treatment of hyperthyroidism
10.3760/cma.j.issn.1008-6706.2015.15.023
- VernacularTitle:131碘治疗甲状腺功能亢进症疗效观察
- Author:
Lingjuan GAO
;
Xuexian SHEN
- Publication Type:Journal Article
- Keywords:
Hyperthyroidism;
Iodine radioisotops
- From:
Chinese Journal of Primary Medicine and Pharmacy
2015;(15):2309-2312
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical effect of iodine-131 treatment of hyperthyroidism.Methods 92 hyperthyroidism patients were selected,who were randomly divided into the observation group and control group, with each 46 cases.The observation group was given radioactive iodine-131 treatment,the control group was given anti thyroid function of drug treatment.The efficacy and adverse drug reaction of the occurrence of long-term and short-term in the two groups were compared.Results In the observation group,the cure rate and total effective rate were respec-tively 93.48% and 100.00%,which were significantly higher than the control group for 63.04% and 84.78%(χ2 =12.55,7.57,all P <0.05).The incidence of adverse reaction in the observation group was 4.35%,which was significantly lower than 21.74% in the control group (χ2 =6.13,P <0.05).The recurrence and complication(hypothyroidism)cases in the observation group,were 1 cases and 8 cases,while the control group were 10 cases and 1 cases.The relapse rate of the observation group was significantly lower than that of the control group,and the incidence of compli-cations was significantly higher than the control group,the difference was statistically significant(χ2 =8.36,6.03,all P <0.05 ).Conclusion The iodine short-term efficacy of-131 in treatment of hyperthyroidism can significantly improve the treatment of the disease,and has high safety,but the complication rate is higher than that of anti thyroid drugs.
