Clinical analysis of 30 cases of drug induced liver injury

VernacularTitle:药物性肝损害30例临床分析
Author: Wenlin SHU ; Zhijian SU
Publication Type:Journal Article
Keywords: Liver injury,drug resistance; Adverse reaction
From: Chinese Journal of Primary Medicine and Pharmacy 2015;(13):2022-2024
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical features and occurrence regularity of drug induced liver injury,so as to provide reference for clinical medication.Methods The choice of hospital 2012 -2014 reported adverse drug reaction monitoring center data,including DILI 30 cases,DILI related data to classify statistics,compre-hensive analysis.Results DILI was of many influence factors,the time of occurrence of large differences,partial onset occult,and related to a drug to immune enhancement agent most(23.33%),followed by anti -tumor drugs (20.00%)and lipid regulating agent(16.67%).Conclusion The medical staff should enhance the understanding of DILI medicine source disease,strengthen the monitoring of adverse drug reactions,as far as possible to reduce the occurrence of DILI,and make its harm to a minimum,reduce the patients pain and medical expenses of disease.