The etiopathogenisis of fungal infections induced by systemic lupus erythematosus
10.3969/j.issn.1006-5725.2015.13.020
- VernacularTitle:系统性红斑狼疮合并真菌感染的特点及诱因
- Author:
Zhen TAN
;
Xiaomei LI
;
Xiangpei LI
;
Guosheng WANG
;
Long QIAN
;
Jinhui TAO
;
Yan MA
- Publication Type:Journal Article
- Keywords:
Lupus erythematosus,systemic;
Fungal infection;
Incentive;
Etiopathogenesis
- From:
The Journal of Practical Medicine
2015;(13):2134-2137
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the etiopathogenisis of fungal infections induced by systemic lupus erythematosus (SLE). Methods One hundred and forty-seven SLE patients with fungal infections during 2004-2013 were assigned as experimental group and the same number of SLE patients without infections were randomly selected as control group. Clinical and laboratory documents of these patients were comparatively analyzed. Results The fungal infections in SLE patients affected oral mucosa , lower respiratory tract and skin , and the pathogenic bacteria were mainly candida albicans. The wide application of glucocorticoid, immunosuppressants and antibiotics pushed the rise of incidence of fungal infections in SLE patients significantly. Conclusions The patients′ use of glucocorticoid , immunosuppressants and antibiotics attributes to a higher risk of fungal infections , especially infections by candida albicans. Fungus infection may raise the level of C4.
