Therapeutic effect analysis of MSM after highly active antiretroviral therapy in Chongqing
10.3969/j.issn.1671-8348.2015.16.016
- VernacularTitle:重庆市男男性行为人群艾滋病患者抗病毒治疗效果分析
- Author:
Chao ZHOU
;
Zongliang CHEN
;
Quanhua ZHOU
;
Guohui WU
;
Ying ZHOU
- Publication Type:Journal Article
- Keywords:
acquired immunodeficiency syndrome;
onsafe sex;
antiviral agents;
treatment outcone
- From:
Chongqing Medicine
2015;(16):2205-2207
- CountryChina
- Language:Chinese
-
Abstract:
Objective To know basic characteristics of MSM infected with HIV treated by highly active antiretroviral thera‐py(HAART) ,and evaluate therapeutic effect based on the level of CD4+ T cell counts .Methods Basic database of patients were collected from the national AIDS comprehensive data information system ,patients were observed by the retrospective cohort study , and effect indicators were analyzed based on the level of CD4+ T cell counts .The data was analyzed by SPSS18 .0 software .Results A total of 1 758 cases were recruited in this study and the average age was (33 .5 ± 11 .1)years .The component ratio of the CD4+T cell counts <50/μL ,50 to 199/μL ,200 to 350/μL ,> 350/μL were 7 .7% ,27 .6% ,54 .9% ,9 .7% ,respectively .The CD4+ T counts increased and kept among 150 to 250/μL ,250 to 350/μL ,350 to 450/μL ,450 to 550/μL ,respectively after 12 months ,treat‐ment .The rates of viral inhibition were 70 .2% ,81 .7% ,84 .2% ,83 .3% ,respectively after 6 months′treatment .And the cumulative survival rates were 0 .81 ,0 .93 ,0 .98 ,1 .0 after 36 ,months treatment ,respectively .Conclusion HAART on MSM achieves remarka‐ble results .And the early treatment was more beneficial to improve immune function ,reduce AIDS mortality and control the HIV/AIDS epidemic of MSM .
