Risk factors for pancreatic cancer in Wenzhou area

VernacularTitle:温州地区胰腺癌发病危险因素分析
Author: Lingyan SHI ; Peichen ZHANG ; Zhimin HUANG ; Chunjing LIN ; Lemei DONG ; Jianshen WU
Publication Type:Journal Article
Keywords: Pancreatic neoplasm; Regression analysis; Risk factors; Logistic models
From: Chinese Journal of Pancreatology 2015;15(3):173-176
CountryChina
Language:Chinese
Abstract: Objective To investigate the risk factors of pancreatic cancer in Wenzhou area.Methods A case control study was conducted on 220 cases with pancreatic cancer and 220 matched controls using conditional logistic regression analysis.Results Univariate analysis showed BMI ＞ 30 kg/m2,smoking,reproductive history,diabetes,cholecystitis,chronic pancreatitis,history of appendectomy,history of partial gastrectomy,history of cancer and familial history of cancer were associated with pancreatic cancer,while multivariate conditional logistic regression analysis showed that the risk factors of pancreatic cancer included smoking (OR =3.624,95％ CI i.474 ～ 8.907),BMI ＞ 30 kg/m2 (OR =1.789,95％ CI 1.030 ～ 3.108),diabetes (OR =3.191,95％ CI 1.094 ～ 9.309),chronic pancreatitis (OR =4.972,95％ CI 1.593 ～ 14.898),and cholecystitis (OR =2.289,95 ％ CI 1.024 ～5.116).Conclusions BMI ＞ 30 kg/m2,smoking and diabetes are risk factors for pancreatic cancer in Wenzhou area.