The diagnostic value of scoring systems in critical acute pancreatitis: a single center retrospective study
10.3760/cma.j.issn.1674-1935.2015.03.001
- VernacularTitle:常用评分方法对危重型急性胰腺炎诊断价值的回顾性单中心临床研究
- Author:
Yuhui CHEN
;
Zhiping XU
;
Dongliang YANG
;
Zhihui TONG
;
Weiqin LI
- Publication Type:Journal Article
- Keywords:
Pancreatitis,acute necrotizing;
Early diagnosis;
Scoring system;
Retrospective studies
- From:
Chinese Journal of Pancreatology
2015;15(3):145-149
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the early diagnostic value of traditional scoring systems in critical acute pancreatitis.Methods From Jan 2007 to Ju12013,consecutive 184 patients with AP who were admitted to the surgical intensive care unit of the Institute of General Surgery,Nanjing Generai Hospital of Najing Militery Region within 72 h from the onset of the disease were studied.Patients were assigned to four groups,including mild,moderate,severe and critical AP according to the determinant based classification and the receiver operating characteristics(ROC) curve was used to predict the presence of critical AP,and Z test and logistic regression was applied to determine the diagnostic value of traditional scoring systems.Results The area under ROC (AUC) of Sofa,BISAP and CTSI score for early diagnosis of critical AP was 0.896,0.877 and 0.862;the best cut off value was 4.5,9.5 and 2.5.Moreover,the AUC of APACHE Ⅱ and Ranson score was 0.807 and 0.707,and the best cut off value was 8.5 and 3.5,respectively.Z test showed early diagnosis rate of Sofa,BISAP,CTSI score was significantly higher than that in Ranson score,and the difference between the two groups was statistically significant (P ＜ 0.05);though they were higher than APACHE Ⅱ score,the difference between the two groups was not statistically significant (P ＞ O.05).Logistic regression showed that high APACHE Ⅱ,Sofa,BISAP and CTSI score were independent risk factors for the development of critical AP (P ＜ 0.05).Conclusions Sofa,CTSI and BISAP score may be clinically important for early diagnosis of critical AP.
