Transient splenial lesion of the corpus callosum in a case of benign convulsion associated with rotaviral gastroenteritis.
10.3345/kjp.2010.53.9.859
- Author:
Yoon Young JANG
1
;
Kye Hyang LEE
Author Information
1. Department of Pediatrics, College of Medicine, Daegu Catholic University, Daegu, Korea. rosalia@cu.ac.kr
- Publication Type:Case Report
- Keywords:
Corpus callosum;
Magnetic resonance imaging;
Diffusion;
Rotavirus infection;
Seizures;
Child
- MeSH:
Asphyxia;
Brain;
Child;
Corpus Callosum;
Diffusion;
Electroencephalography;
Encephalitis;
Follow-Up Studies;
Gastroenteritis;
Humans;
Magnetic Resonance Imaging;
Magnetic Resonance Spectroscopy;
Neuroimaging;
Prognosis;
Rotavirus;
Rotavirus Infections;
Seizures
- From:Korean Journal of Pediatrics
2010;53(9):859-862
- CountryRepublic of Korea
- Language:English
-
Abstract:
Transient magnetic resonance (MR) signal changes in the splenium of the corpus callosum (SCC) arise from many different conditions, including encephalopathy or encephalitis caused by infection, seizures, metabolic derangements, and asphyxia. Few case reports exist on reversible SCC lesions associated with rotavirus infection. A benign convulsion with mild gastroenteritis (CwG) is frequently associated with rotaviral infections. This entity is characterized by normal laboratory findings, electroencephalogram, neuroimaging, and good prognosis. We report a case of a 2.5-year-old Korean girl with rotavirus-associated CwG demonstrating a reversible SCC lesion on diffusion-weighted MR images. She developed 2 episodes of brief generalized tonic-clonic seizure with mild acute gastroenteritis without any other neurologic abnormality. Stool test for rotavirus antigen was positive. Brain MRI done on the day of admission showed a linear high signal intensity and decreased apparent diffusion coefficient values on the SCC. The lesion completely disappeared on follow-up MRI 6 days later. The patient fully recovered without any sequelae.