The clinical value of cardiac troponin Ⅰ in patients with unstable angina pectoris and minor myocardial damage
10.3760/cma.j.issn.1673-4904.2014.31.015
- VernacularTitle:心肌肌钙蛋白Ⅰ测定对于不稳定型心绞痛患者微小心肌损伤的临床价值
- Author:
Xiaowei WANG
;
Dalin JIA
;
Guoxian QI
- Publication Type:Journal Article
- Keywords:
Troponin;
Angina,unstable;
Prognosis;
Minor myocardial damage
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(31):41-43
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the clinical value of serum cardiac troponin Ⅰ (cTnⅠ) in patients with unstable angina pectoris (UAP) and minor myocardial damage.Methods The serum cTnⅠ level of 60 UAP patients (UAP group) were determined.The patients whose cTnⅠ were ≥ 0.1 μ g/L were ascribed to cTnⅠ positive group,and the patients whose cTnⅠ were ＜ 0.1 μ g/L were ascribed to cTnⅠ negative group.The correlation among clinical data,coronary arterial lesions and adverse cardiac events were analyzed.Forty healthy people were selected as control group.Results The positive rate of cTnⅠ in UAP group (35.0％,21/60) was significantly higher than that in control group (0),and there was statistical difference (P ＜ 0.01).The incidence rate of coronary arterial multi-branch lesions and/or severe stenosis in cTnⅠ positive group (19.0％,4/21) was higher than that in cTnⅠ negative group (5.1％,2/39),but there was no statistical difference (P ＞ 0.05).The incidence rate of 90 d adverse cardiac events in cTnⅠ positive group (33.3％,7/21) was significantly higher than that in cTnⅠ negative group (5.1％,2/39),and there was statistical difference (P ＜ 0.01).Conclusions Low-level cTnⅠ demonstrates minor myocardial damage sensitively and specifically.cTnⅠ level detected quantitatively can help to assess prognosis and provide risk stratification of UAP patients.
