The relationship between serum pregnancy associated plasma protein A level and pregnancy outcomes in early pregnancy
10.3760/cma.j.issn.1673-4904.2014.30.017
- VernacularTitle:孕早期血清妊娠相关血浆蛋白A水平与妊娠结局关系的研究
- Author:
Huanyi GUO
;
Xiujie SHENG
- Publication Type:Journal Article
- Keywords:
Abortion,threatened;
Pregnancy-associated plasma protein-A;
Pregnancy outcome
- From:
Chinese Journal of Postgraduates of Medicine
2014;37(30):50-53
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the relationship between pregnancy associated plasma protein A (PAPP-A) and threatened abortion,whether low level of PAPP-A in early pregnancy can be used as indicators to predict the pregnancy outcomes.Methods The level of serum PAPP-A was measured by double antibody sandwich enzyme-linked immunosorbent assay in 110 cases with threatened abortion (threatened abortion group) and 131 cases with normal intrauterine pregnancy (control group),and track to 20 weeks pregnant.Results The serum PAPP-A multiple of median (MOM) value was 1.02 ± 0.15 in control group,0.98 ± 0.17 in threatened abortion group,and there was no significant difference(P ＞ 0.05).In threatened abortion group,90 cases of spuc success,the serum PAPP-A MOM value was 1.03 ± 0.11,20 patients of spuc failure,the serum PAPP-A MOM value was 0.73±0.21,and there was significant difference (P ＜ 0.01).There was no significant difference in the serum PAPP-A MOM value between control group and the spuc success of threatened abortion group (P ＞ 0.05).Conclusion Pregnant women with PAPP-A levels embryonic development is closely related to the good,as one can predict miscarriage in pregnant women with threatened abortion outcome evaluation.
