Aggressive systemic mastocytosis:one case report and literatures review

VernacularTitle:侵袭性系统性肥大细胞增生症一例并文献复习
Author: Yi LI ; Wenyu CAI ; Tiejun QIN ; Yue ZHANG ; Zefeng XU ; Zhijian XIAO
Publication Type:Journal Article
Keywords: Mastocytosis,systemic; Risk factor; Treatment
From: Journal of Leukemia & Lymphoma 2014;23(8):488-491
CountryChina
Language:Chinese
Abstract: Objective To improve the acknowledge of diagnosis and therapy of aggressive systemic mastocytosis (ASM).Methods One ASM patient was reported and the literatures were reviewed.Results As a rare subtype of SM,ASM is characterized by multiple organs involvement,and often accompanied by bone marrow dysfunction,osteolytic lesions and palpable hepatomegaly or splenomegaly which usually indicate the high mast cell burden.Conclusion ASM meets criteria for SM and has one or more C findings.Variable factors affect the prognosis of ASM patients and the formulation of the clinical treatment strategy which leads to the highly individualized therapies.