Clinical characteristics and treatment analysis of 51 cases of primary gastric non-Hodgkin lymphoma

VernacularTitle:原发胃非霍奇金淋巴瘤51例临床特点及治疗分析
Author: Yuehua HUANG ; Daobin ZHOU ; Minghui DUAN ; Jian LI ; Junling ZHUANG ; Bing HAN ; Wei ZHANG
Publication Type:Journal Article
Keywords: Neoplasms,primary; Stomach neoplasms; Lymphoma,non-Hodgkin; Prognosis; Progress free survival; Overall survival
From: Journal of Leukemia & Lymphoma 2014;23(6):339-342
CountryChina
Language:Chinese
Abstract: Objective To investigate the clinical characteristics and prognostic factors in patients with primary gastric non-Hodgkin lymphoma (PG-NHL).Methods The pathological data of 51 PG-NHL patients admitted in our hospital from 2003 to 2013 were analyzed retrospectively.Results In 51 patients with PG-NHL,there were 26 males and 25 females.The patients' age ranged from 18 to 80 years old with median age as 56 years old.The median survival time was 32 months (range from 1 to 114 months).The oneyear overall survival (OS),three-year OS and five-year OS were 90.2 ％,82.4 ％ and 80.4 ％,respectively.The surgery did not significantly improve PG-NHL patients' progress free survival and OS.Only 1 (2.0 ％) patient had gastrointestinal hemorrhage and perforation after chemotherapy.However,6 (46.2 ％) patients suffered from early satiety,gastric emptying disorder,alkaline reflux gastritis and dumping syndrome in surgery group.Conclusions Surgery did not improve the survival of PG-NHL patients.The life quality in chemotherapygroup is better than that in surgical group.