Progress of clinical transformation research in malignant lymphoma in 2013
10.3760/cma.j.issn.1009-9921.2014.03.004
- VernacularTitle:2013年度淋巴瘤临床转化研究领域的新进展
- Author:
Ning DING
;
Jun ZHU
- Publication Type:Journal Article
- Keywords:
Lymphoma,non-Hodgkin;
Signal pathway;
Mutation;
Targeted drug
- From:
Journal of Leukemia & Lymphoma
2014;23(3):141-143
- CountryChina
- Language:Chinese
-
Abstract:
Advances in clinical transformation research has facilitated discovery of a number of novel somatic mutations and aberrant intracellular signaling pathways involved in malignant proliferative B-cell lymphoma.Meanwhile,small molecular inhibitors targeting those mutation genes or signaling pathways have also been shown to be effective in treating relapsed and refractory B-cell non-Hodgkin lymphoma.This paper reviewed important discoveries in clinical transformation research in lymphoma field in 2013.
