Monoclonal gammopathy of undetermined significance and smoldering multiple myeloma: biological insights and early treatment strategies
10.3760/cma.j.issn.1009-9921.2014.05.001
- VernacularTitle:意义未明的单克隆丙种球蛋白血症和冒烟型骨髓瘤:生物学特征与早期治疗策略
- Author:
Yuan JIAN
;
Dong YAN
;
Wenming CHEN
- Publication Type:Journal Article
- Keywords:
Multiple myeloma;
Monoclonal gammopathy of undetermined significance;
Smoldering multiple myeloma
- From:
Journal of Leukemia & Lymphoma
2014;23(5):257-260
- CountryChina
- Language:Chinese
-
Abstract:
Researches on monoclonal gammopathy of undetermined significance (MGUS) and smoldering muhiple myeloma (SMM) are at a low level although their incidence is high.This review discusses curent biological insights in MGUS/SMM and discusses how the integration of novel biological markers,molecular imaging,and clinical monitoring of MGUS/SMM could facilitate the development of early treatment strategies for high-risk SMM (early myeloma) patients in the future.