Research progress of the 8p11 myeloproliferative syndrome
10.3760/cma.j.issn.1009-9921.2013.12.019
- VernacularTitle:8p11骨髓增殖综合征的研究进展
- Author:
Yujie JIANG
- Publication Type:Journal Article
- Keywords:
8p11 myeloproliferative syndrome;
Fibroblast growth factor receptor 1;
Hematopoietic stem cell transplantation
- From:
Journal of Leukemia & Lymphoma
2013;22(12):758-761
- CountryChina
- Language:Chinese
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Abstract:
The 8p11 myeloproliferative syndrome is a rare hematologic malignancy that involves the fibroblast growth factor receptor 1 (FGFR1) gene at chromosome 8p11.The clonal change of the FGFR1 rearrangement is present in BM cells,and in the T-lymphoma cells in the LN.The hematological stem cells transplantation is the only method that can cure this rare hematologic neoplasma.