The giant neurofibroma of penis in a child: a case report and literature review
10.3760/cma.j.issn.2095-428X.2015.07.019
- VernacularTitle:小儿巨大阴茎神经纤维瘤1例并文献复习
- Author:
Chengwei CHAI
;
Guochang LIU
;
Daorui QIN
;
Fenghua WANG
;
Jiahang ZENG
;
Huilin NIU
- Publication Type:Journal Article
- Keywords:
Neurofibroma;
Neurofibromatosis;
Penis;
Treatment
- From:
Chinese Journal of Applied Clinical Pediatrics
2015;30(7):549-551
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical and pathological characteristics,diagnosis,differential diagnosis,treatment and prognosis of giant neurofibroma of penis in the child.Methods The clinical data including general data,imaging data,treatment methods,pathological characteristics of a case with giant neurofibroma of penis in a child were analyzed retrospectively and the relevant literature was reviewed.Results Gross appearance of the penile shaft neurofibroma was about 9 cm × 11 cm × 15 cm,with local ulceration.Computerized tomography scan revealed a giant mass in the penile shaft,about 9.0 cm × 10.0 cm × 13.4 cm.Partial excision of the penis was performed.Postoperative appearance of the residual penile shaft was about 2 cm long.The HE staining showed spindle cells with the red dye cytoplasm,spindle or elliptic nuclei and arranged in wavy partly.Positive immunostaining was presented with S-100 protein and Vimentin.The pathologic examination revealed a neurofibroma.There was no evidence of recurrence and the penis of the boy had normal sensation and erection by follow-up in 2 years.Conclusions Neurofibroma of penis in the child is extremely rare and the differential diagnosis of soft-tissue tumors of penis should be considered.The operative method should be individualized,the treatment goal is the complete resection;however,this goal must be weighed against detriment to functioning and the cosmetics of the involved organ.
