Research progress of predictive markers of multiple sclerosis after a clinically isolated syndrome
10.3760/cma.j.issn.2095-428X.2015.06.020
- VernacularTitle:预测临床孤立综合征转化为多发性硬化相关指标的研究进展
- Author:
Yan JIANG
;
Li JIANG
- Publication Type:Journal Article
- Keywords:
Clinically isolated syndrome;
Multiple sclerosis;
Conversion;
Prediction
- From:
Chinese Journal of Applied Clinical Pediatrics
2015;30(6):473-475
- CountryChina
- Language:Chinese
-
Abstract:
A clinically isolated syndrome(CIS) is a term that describes a first clinical episode in which a patient has symptoms and signs suggestive of an inflammatory demyelinating disorder of the central nervous system.And it often affects optic nerves,the brainstem,or the spinal cord,and 30％-70％ of the CIS patients may develop multiple sclerosis(MS).Disease-modifying treatments may delay the development from CIS to MS.Their use in CIS is limited because of uncertain long-term clinical prognosis,treatment benefits and adverse effects.This article reviews the advances of predictive markers of conversion to MS after a CIS,in order to provide the reference for clinical treatment.
