Research progress of transmembrane protein 16a in cardiovascular system
10.3760/cma.j.issn.2095-428X.2015.01.019
- VernacularTitle:跨膜蛋白16a在心血管系统中的研究进展
- Author:
Qiaoyun TANG
;
Yusheng PANG
;
Kai WANG
- Publication Type:Journal Article
- Keywords:
Transmembrane protein 16a;
Calcium-activated chloride channels;
Cardiovascular system
- From:
Chinese Journal of Applied Clinical Pediatrics
2015;30(1):75-77
- CountryChina
- Language:Chinese
-
Abstract:
Calcium-activated chloride channels(CaCCs) play an important role in cardiovascular system,including participating in a variety of physiological functions and being associated with the pathology progress of many cardiovascular diseases.With the development of research,transmembrane protein 16a (TMEM16A) has recently been identified as the molecular basis of CaCCs.Since the study of TMEM16A has got some achievement,especially in the section of cardiovascular system,its main research progress and key points from previous researches are summarized,in which the expression and physiological function of TMEM16A,as well as its clinical pathological correlations with some cardiovascular diseases are told about.Besides,the research prospect of TMEM16A in targeting therapy of cardiovascular disease is also discussed.
