Laboratory examination of autoimmune and autoinflammatory diseases
10.3760/cma.j.issn.2095-428X.2015.09.005
- VernacularTitle:自身免疫与炎症性疾病的实验室检查
- Author:
Qiuye ZHANG
;
Cui BAI
- Publication Type:Journal Article
- Keywords:
Autoimmune disease;
Autoinflammatory disease;
Laboratory examination
- From:
Chinese Journal of Applied Clinical Pediatrics
2015;30(9):653-658
- CountryChina
- Language:Chinese
-
Abstract:
Autoimmune disease is an own organization inflammatory lesions,mainly caused by destroying the adaptive immune tolerance mechanism of differentiatingself andnon-self,whose character is appearing the autoantibodies and self-reactive T cells in the body.Autoinflammatory disease is a group of genetic,recurrent and noninvasive inflammatory disease,whose characteristics are fever,rash,joint pain,arthritis,ophthalmic pathological changes and increasing of acute phase proteins,and it can affect many organ systems.These diseases are different in the mode of onset and clinical manifestations,but also can have similar and overlapped symptoms and signs,and often confused with other systemic diseases.Therefore,clinical misdiagnoses or missed diagnoses easily occur.To understand correctly and master the laboratory examination characteristics and its clinical is essential,which has significant value in the clinical diagnosis,differential diagnosis,evaluation and treatment of these diseases.