The correlation of serum lipids changes with the staging and classification in gastric cancers
10.3760/cma.j.issn.1008-1372.2014.09.020
- VernacularTitle:血脂变化与胃癌分期和分型的关系
- Author:
Qun LIU
;
Yunxiu HOU
;
Lai WU
- Publication Type:Journal Article
- Keywords:
Cholesterol/blood;
Lipoproteins,HDL/blood;
Lipoproteins,LDL/blood;
Stomach neoplasms/pathology;
Neoplasm staging;
Prognosis
- From:
Journal of Chinese Physician
2014;16(9):1227-1229
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlations of the levels of serum total cholesterol (TC),high density lipoprotein(HDL),and low density lipoprotein (LDL) with tumor node metastasis (TNM) staging and Lauren's classification in gastric cancer.Methods The blood lipid levels of 157 cases of gastric cancers,80 cases of benign gastric diseases,and 80 cases of normal subjects were detected by the Hitachi 7170A automatic biochemical instrument,and these values were statistically compared with SPSS 19.0.Results The contents of serum TC,HDL,and LDL in the group of gastric cancers were lower than those in the groups of normal subjects and benign gastric diseases (P ＜ 0.05).The contents of serum HDL levels were decreased with the increase of the TNM stage in patients with gastric cancer,and were all lower than the benign gastric diseases and the health control group (P ＜ 0.05).No statistically significant correlation was found in the levels of serum TC,HDL,and LDL in Lauren's histological types of gastric cancers (P ＜0.05).Conclusions Abnormal lipid metabolism had already appeared in gastric cancer,and the decreased serum HDL levels was correlated with TNM stage of gastric cancer.Detection of the changes of lipid levels in patients might be beneficial to the screening and prognosis of gastric cancer.
