Advances in hematopoietic stem cell mobilization
10.3760/cma.j.issn.1009-9921.2013.07.007
- VernacularTitle:造血干细胞动员的进展
- Author:
Jiacai ZHUO
- Publication Type:Journal Article
- Keywords:
Hematopoietic stem cell;
Mobilization
- From:
Journal of Leukemia & Lymphoma
2013;22(7):400-405
- CountryChina
- Language:Chinese
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Abstract:
Mobilized peripheral blood stem cells (PBSC) have largely replaced the use of bone marrow as a source of stem cells for both allogeneic and autologous stem cell transplantation.G-CSF with or without chemotherapy is the most commonly used regimen for stem cell mobilization.Some donors or patients,especially the heavily pretreated patients,fail to mobilize the targeted number of stem cells with this regimen.The generation of new mobilization agents and new therapies can improve the mobilization of hematopoietic stem cells.
