Research progress in the biology of Hodgkin's lymphoma in the 54th ASH annual meeting
10.3760/cma.j.issn.1009-9921.2013.07.001
- VernacularTitle:第54届美国血液学会年会霍奇金淋巴瘤生物学研究领域的主要进展
- Author:
Wei ZHANG
;
Jing WANG
;
Xiaoyan KE
- Publication Type:Journal Article
- Keywords:
Lymphoma,Hodgkin's;
Biology;
ASH annual meeting
- From:
Journal of Leukemia & Lymphoma
2013;22(7):385-386
- CountryChina
- Language:Chinese
-
Abstract:
The Hodgkin and Reed/Sternberg (HRS) tumor cells of classical Hodgkin's lymphoma (HL) and the lymphocyte-predominant (LP) tumor cells of nodular lymphocyte-predominant HL are both derived from germinal center B cells.Several studies show that HL pathogenesis includes the deregulated activity of numerous members and regulators of the NF-κB and JAK/STAT signaling pathways,genetic lesions of epigenetic regulators,and the interactions between tumor cells and other infiltrating cells in the microenvironment,et al.
