Transforming growth factor-β and tumor
10.3760/cma.j.issn.1673-422X.2015.01.011
- VernacularTitle:转化生长因子-β与肿瘤
- Author:
Nailing TANG
;
Zhi GUO
;
Xueling YANG
- Publication Type:Journal Article
- Keywords:
Transforming growth factor β;
Neoplasms;
Inhibitors
- From:
Journal of International Oncology
2015;42(1):43-45
- CountryChina
- Language:Chinese
-
Abstract:
Many studies show that transforming growth factor-β (TGF-β) can suppress tumor by inhibiting proliferation and dedifferentiation of cells and promoting cell apoptosis at early stage.But during the progression of tumor,its tumor-promoting action will be more and more obvious with the variation of TGF-β itself and its signal path.TGF-β signal path inhibitors have anti-tumor activity,but the clinical effects and side effects still need to be observed.
