Function of Toll like receptor signaling pathway in the carcinogenesis process related to high risk HPV infection of cervical
10.3760/cma.j.issn.1673-422X.2014.11.013
- VernacularTitle:Toll样受体信号通路在宫颈高危HPV感染致癌过程中的相关功能
- Author:
Xiaoxian XU
;
Hanmei LOU
- Publication Type:Journal Article
- Keywords:
Uterine cervical neoplasms;
Papillomavirus infections;
Toll-like receptors
- From:
Journal of International Oncology
2014;41(11):840-843
- CountryChina
- Language:Chinese
-
Abstract:
Toll like receptors (TLRs) are the most characteristic of pathogen recognition receptors.TLR signal pathway affects the outcome of cervical HPV infection,and plays double roles of promoting or inhibiting tumor in immune regulation for the process from high-risk HPV infection to cervical cancer.The polymorphism of TLR gene is closely related to the occurrence of cervical cancer.