Cyclin-dependent kinase 10 and tumorigenesis
10.3760/cma.j.issn.1673-422X.2014.11.004
- VernacularTitle:周期素依赖性激酶10与肿瘤发生
- Author:
Yanjie YOU
;
Wenmei LI
;
Jiajia LIU
;
Yi YUAN
- Publication Type:Journal Article
- Keywords:
Genes,tumor suppressor;
Neoplasms;
Tumor markers,biological;
Diagnosis
- From:
Journal of International Oncology
2014;41(11):811-812
- CountryChina
- Language:Chinese
-
Abstract:
Cyclin-dependent kinase 10 (CDK10) function as a tumor suppressor gene through regulating cell cycle interacting with transcription factor Ets2.Studies demonstrate that the downregulation of CDK10 expression occurs in multiple cancer types,indicating a potential application of CDK10 as a molecular diagnostic marker as well as therapeutic target.
