Nano targeted drug delivery system and the treatment of oral cancer
10.3760/cma.j.issn.1673-422X.2014.10.011
- VernacularTitle:纳米靶向给药系统与口腔癌治疗
- Author:
Ping MA
;
Wulong JIN
- Publication Type:Journal Article
- Keywords:
Nanotechnology;
Drug therapy;
Mouth neoplasms;
Drug delivery systems
- From:
Journal of International Oncology
2014;41(10):753-756
- CountryChina
- Language:Chinese
-
Abstract:
Oral cancer is one of the most common malignant tumor of the head and neck.Passive targeting is a targeted therapy for initial treatment of oral cancer,which is not always effective.In order to achieve better targeted therapy on oral cancer,researchers have turned to the study of active targeting with nano drug delivery system in recent years.With this treatment,nanoparticles are attached to the surface of the target molecules,and combine with specific expression or overexpression receptor on the surface of tumor cell to achieve target.This delivery system can transport anticancer drugs directed at the lesion site and achieve the purpose of reducing adverse drug reaction and increasing treatment efficacy.Targeted chemotherapy is increasing being used in the treatment of oral cancer.