LASS family and tumor
10.3760/cma.j.issn.1673-422X.2014.10.005
- VernacularTitle:LASS家族和肿瘤
- Author:
Tao XIONG
;
Haifeng WANG
;
Jiansong WANG
- Publication Type:Journal Article
- Keywords:
Ceramides;
Genes,tumor suppressor;
Neoplastic process
- From:
Journal of International Oncology
2014;41(10):734-736
- CountryChina
- Language:Chinese
-
Abstract:
LASS gene family is a group of highly conserved and longevous gene LASS protein has a ceramide synthase activity,which can synthesize different types of ceramides.Ceramide is a key intermediate in tumor cells growth,signal transduction and other aspects.Thus it is inferred that the expression of LASS gene can suppress the occurrence and development of tumor within a certain range.
