Self-renewal mechanism of cancer stem cells
10.3760/cma.j.issn.1673-422X.2014.12.006
- VernacularTitle:肿瘤干细胞的自我更新机制
- Author:
Tong WANG
;
Xiaofei QI
;
Ri ZHANG
- Publication Type:Journal Article
- Keywords:
Neoplasms;
Neoplastic stem cells;
Polycomb group proteins;
Signal transduction
- From:
Journal of International Oncology
2014;41(12):896-898
- CountryChina
- Language:Chinese
-
Abstract:
Cancer stem cells comprise a sub-population with the capacity of self-renewal,self-differentiation and high tumorigenicity.Cancerogenesis,development,relapse and therapeutic resistance are closely related with these cells.The most important characteristics of these cells are the ability to self-renew.So insight into the regulating mechanism of self-renewal in cancer stem cells will be important for the development of novel molecular agents targeted the cancer stem cells.
