Matrix metalloproteinase-9 and blood-brain barrier damage and neurovascular remodeling after cerebral ischemia
10.3760/cma.j.issn.1673-4165.2014.08.010
- VernacularTitle:基质金属蛋白酶-9与脑缺血后血脑屏障破坏和神经血管重塑
- Author:
Li SHAN
;
Qiang MENG
- Publication Type:Journal Article
- Keywords:
Stroke;
Brain Ischemia;
Matrix Metalloproteinase 9;
Blood-Brain Barrier;
Neovascularization,Physiologic;
Neurogenesis;
Neuroprotective Agents
- From:
International Journal of Cerebrovascular Diseases
2014;22(8):629-632
- CountryChina
- Language:Chinese
-
Abstract:
Matrix metalloproteinase-9 plays an important role in the blood-brain barrier disruption.Blood-brain barrier disruption may directly influence the neurovascuiar unit repair after cerebral ischemia.An in-depth study of matrix metalloproteinase-9-mediated ischemic brain damage and neurovascular remodeling is expected to open up a new way for the diagnosis and treatment of cerebral ischemia in clinical practice.
