Female bladder ectopic skene glands: one case report and literature review
10.3760/cma.j.issn.1000-6702.2015.02.013
- VernacularTitle:女性膀胱异位Skene腺体一例报告并文献复习
- Author:
Yashi RUAN
;
Wei GUO
;
Tianli NIU
;
Wei XIAO
;
Hong YU
;
Min BIAN
- Publication Type:Journal Article
- Keywords:
Female;
Urinary bladder neoplasms;
Ectopic skene glands;
Ectopic prostate tissue;
Pathology
- From:
Chinese Journal of Urology
2015;36(2):131-134
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the pathological and immunohistochemical characteristics of female bladder ectopic skene glands.Methods A female with bladder tumor was treated in our hospital in May 2013.Preoperative so(n)graphy revealed a 0.9 cm×0.6 cm round solid mass in the bottom of bladder wall.Mass was hypoechoic homogeneous with regular shape,blood flow within the mass was noted.The tumor was treated with transurethral resection.Routine pathological examination suggested bladder ectopic Skene glands.Immunohistochemical stains for prostate specific antigen (PSA),prostate spectific acid phosphatase (PSAP),androgen receptor (AR),estrogen receptor (ER),CD10,cytokeratin 14 (CK14),cytokeratin 18 (CK18),P63,high molecular weight cytokeratin (34βE12),α-methylacyl-CoA racemase (AMACR/p504s) were further performed.Results Routine pathological examination showed prostate glands composed of prostate gland epithelial cells and basal cells in a submucosal location.Immunohistochemical stains showed:PSA-,PSAP +,AR +,ER-,CD10+,CK18 +,CK14-,P63 +,34βE12 +,AMACR-.Conclusions Routine pathological examination combined with immunohistochemical stains such as PSA,PSAP,and others,can be used to diagnose ectopic Skene glands disease.Female bladder ectopic Skene glands is a benign lesion,and the prognosis is good.
